• TOPIX  |  WEDNESDAY, MAY 17, 2017
    [Glucagon] Research opens the door to improved drugs for type 2 diabetes
    IMAGE: Beam me up: The new Nature study reports the crystal structure of the full-length human glucagon receptor that plays a key role in glucose homeostasis and serves as an. view Type 2 diabetes, a prolific killer, is on a steep ascent. According to the World Health Organization, the incidence of the condition has grown dramatically from 108 million cases in 1980 to well over 400 million today
  • SCIENCE DAILY  |  WEDNESDAY, MAY 17, 2017
    [Glucagon] Improving drugs for type 2 diabetes
    Their findings shed new light on the structure of the glucagon receptor, a highly promising target for diabetes drug development Scientists are exploring a central component in glucose regulation.
  • INSULIN NATION  |  THURSDAY, APRIL 20, 2017
    [Glucagon] Victoza Tested to Combat DKA for People with Type 1
    GLP-1 drugs work by slowing the body’s glucagon production, increasing insulin production (when possible), and slowing the rate by which food leaves the stomach. Researchers found that those who received Victoza had lower levels of glucagon, ghrelin (a hormone that increases appetite), and free fatty acids that could lead to diabetic ketoacidosis, according to a report in MedPage Today.
  • SCIENCE DAILY  |  TUESDAY, APRIL 11, 2017
    [Glucagon] Premature cell differentiation leads to disorders in pancreatic development
    The mutation causes the pancreatic cells that produce glucagon and insulin to differentiate too early A mechanism through which a mutation in the STAT3 gene leads to a disorder in the development of the pancreas and to infant diabetes has now been identified by researchers.
  • INSULIN NATION  |  FRIDAY, APRIL 7, 2017
    [Glucagon] Endocrinologist Says She Can’t Compete to Artificial Pancreas
    Eventually, researchers hope to fully automate insulin delivery and add glucagon delivery. At a recent JDRF Type One Nation summit in Hartford, Connecticut, an endocrinologist gave her personal perspective of efforts to develop artificial pancreas pump systems. Dr. Jennifer Sher, an assistant professor of pediatric endocrinology at the Yale School of Medicine, has been involved in artificial pancreas technology since the early stages of this field of research. sponsor.
  • TOPIX  |  SATURDAY, MARCH 25, 2017
    [Glucagon] Diabetes Management: Combined Treatment with Insulin/GLP-1 Receptor Agonists
    A Pharmacy Times Continuing Education session presented at the American Pharmacists Association's 2017 Annual Meeting & Exposition in San Francisco provided a clinical discussion on data associated with combining basal insulin with glucagon-like peptide-1 receptor agonist and the insulin combination products to achieve and maintain glycemic control in patients with type 2 diabetes.
  • INSULIN NATION  |  MONDAY, MARCH 20, 2017
    [Glucagon] Insulin Pump Helps Woman Escape Kidnapping
    If you have any instances when diabetes needles, meters, pumps, CGMs, or glucagon kits were used in such a situation, I’d love to hear about it. sponsor. In an incredible turn of events, a nursing student with diabetes escaped a kidnapping because she was wearing an insulin pump. According to a report on the TODAY Show, Brittany Diggs was abducted outside her apartment in Birmingham, Alabama.
  • INSULIN NATION  |  WEDNESDAY, FEBRUARY 15, 2017
    [Glucagon] NIH Funds Four Artificial Pancreas Trials
    These trials will focus on fully automated insulin delivery systems, as well as an automated insulin and glucagon delivery system. This is the big home-stretch study to get Beta Bionics’ glucagon and insulin pump system to the finish line of applying for FDA pre-market approval. In February 2017, the National Institutes of Health (NIH) announced that it has funded four important trials of artificial pancreas technology, and that the first of the four trials was already underway.
  • INSULIN NATION  |  TUESDAY, FEBRUARY 14, 2017
    [Glucagon] Ketones and Exercise – What You Need to Know
    In Type 1 diabetes, ketone levels can rise even without starvation, if insulin levels drop too much and levels of other hormones like glucagon and catecholamines rise. This may be because this new class of medications drops insulin needs to very low levels and may increase glucagon levels. In a new set of guidelines for Type 1 diabetes and exercise, I and my fellow researchers warn that people with Type 1 diabetes need to monitor for elevated levels of ketones during exercise.
  • INSULIN NATION  |  WEDNESDAY, FEBRUARY 8, 2017
    [Glucagon] 25 Facts to Know on Exercise on Type 1 Diabetes
    During aerobic exercise, insulin secretion decreases and glucagon secretion increases. This past month, researchers from more than a dozen leading diabetes and exercise research teams published guidelines on how to exercise with Type 1 diabetes. These guidelines, published in the Lancet, represent the current international consensus of the best methods for maintaining blood sugar control with exercise.
  • INSULIN NATION  |  WEDNESDAY, FEBRUARY 8, 2017
    [Glucagon] 25 New Recommendations on Exercise on Type 1 Diabetes
    During aerobic exercise, insulin secretion decreases and glucagon secretion increases. This past month, researchers from more than a dozen leading diabetes and exercise research teams published guidelines on how to exercise with Type 1 diabetes. These guidelines, published in the Lancet, represent the current international consensus of the best methods for maintaining blood sugar control with exercise.
  • TOPIX  |  FRIDAY, FEBRUARY 3, 2017
    [Glucagon] 1.05m grant to Cambridge diabetes firm
    Arecor's liquid glucagon is an important addition to its speciality diabetes pipeline and will offer a vastly superior glucagon rescue treatment for severe hypoglycaemia and may have further applications in enabling dual hormone artificial pancreas systems Arecor, the company on Chesterton Research Park developing better treatments for diabetes, has been awarded a 1.05m government grant to help push ahead to early stage clinical trials.
  • TOPIX  |  TUESDAY, JANUARY 17, 2017
    [Glucagon] Investigational Semaglutide Tied to Improved Glucose Control in Type 2 Diabetes
    Semaglutide, a glucagon-like peptide-1 receptor agonist, is associated with improvements in glucose control in adults with type 2 diabetes, according to the phase IIIa, industry-funded SUSTAIN 1 trial published in the Lancet Diabetes & Endocrinology.
  • TOPIX  |  SUNDAY, JANUARY 8, 2017
    [Glucagon] Dipeptidyl peptidase-4 inhibition by Saxagliptin prevents.
    Glucagon-like peptide-1 receptor activation delays the progression of diabetic nephropathy in rodents. The NOD-like receptor 3 inflammasome plays an important role in DN
  • TOPIX  |  THURSDAY, JANUARY 5, 2017
    [Glucagon] YMCA Alleged Discrimination Settlement Reached
    The settlement agreement requires the YMCA of Metro Chicago to administer the emergency medicine glucagon to program enrollees with Diabetes who have requested it A settlement has been reached between the United States Attorney's Office and the YMCA of Metro Chicago that resolves a complaint of discrimination filed on behalf of a child with type 1 Diabetes.
  • TOPIX  |  WEDNESDAY, JANUARY 4, 2017
    [Glucagon] YMCA in Chicago settles discrimination complaint
    She'd been told staff couldn't administer an emergency shot called glucagon for low blood sugar, and she would need to be accompanied by a family member who could give the shot The complaint was filed on behalf of a 9-year-old girl with diabetes on a YMCA swim team.
  • INSULIN NATION  |  THURSDAY, DECEMBER 29, 2016
    [Glucagon] 20 Questions to Ask a New Endocrinologist
    When would you recommend glucagon? This edited excerpt is from The Savvy Diabetic – A Survival Guide (reprinted by permission): You can, and should, ask to meet an endocrinologist or doctor before you choose to become a patient in their practice. Most often, doctors will give you 15 minutes to meet and ask questions. Think of it as a speed-date. sponsor. Here are some questions you might want to ask a doctor during this initial visit: 1. What is your experience with Type 1 diabetes?
  • INSULIN NATION  |  THURSDAY, DECEMBER 29, 2016
    [Glucagon] 20 Questions Every Person with Type 1 Should Ask a New Endocrinologist
    When would you recommend glucagon? This edited excerpt is from The Savvy Diabetic – A Survival Guide (reprinted by permission): You can, and should, ask to meet an endocrinologist or doctor before you choose to become a patient in their practice. Most often, doctors will give you 15 minutes to meet and ask questions. Think of it as a speed-date. sponsor. Here are some questions you might want to ask a doctor during this initial visit: 1. What is your experience with Type 1 diabetes?
  • TOPIX  |  THURSDAY, DECEMBER 22, 2016
    [Glucagon] Diabetes News: Anti-Malaria Drug Turns Glucagon-Producing Alpha.
    DIABETES NEWS: Anti-Malaria Drug Turns Glucagon-Producing Alpha Cells into Insulin-Producing Beta Cells. The results of this study, which was partially funded by the JDRF have been published in the journal Cell and indicate that diabetic fish, mice, and rats were all treated successfully with artemisinins
  • INSULIN NATION  |  WEDNESDAY, DECEMBER 14, 2016
    [Glucagon] 2016 Was the Last Best Year for the Artificial Pancreas
    An initial 11-day trial in a real world setting proved the insulin-and-glucagon system’s safety and effectiveness. (If There were major advancements in automated insulin delivery this year, and also a large debate over the name for such a system. We will look back at 2016 as the year that the artificial pancreas went from the theoretical to the practical, as the FDA approved at least one artificial pancreas system, at least in air quotes.
  • TOPIX  |  TUESDAY, DECEMBER 6, 2016
    [Glucagon] Novo Nordisk Files for Regulatory Approval of Once-Weekly Semaglutide for Type-2 Diabetes
    Novo Nordisk has submitted a new drug application to the FDA for semaglutide, a glucagon-like peptide-1 analogue administered once weekly for the treatment of adults with type-2 diabetes. The submission was based on results from the SUSTAIN clinical trial program, which included eight phase 3a studies involving more than 8,000 adults with T2D
  • D-MOM  |  SUNDAY, DECEMBER 4, 2016
    [Glucagon] {3 Little Diabetes Things} 12.04.2016
    We are always on the hunt for a bag that will hold Q’s pump, low supplies, glucagon, her phone, and her CGM without being too big. I sometimes have a “little” something to say about diabetes. Today I’m sharing three products that Q has been using. Sugar Medical Callie Crossbody Bag*. Q also likes wearing purses across her body. And that’s how my husband wears it when he takes the load off her.
  • TOPIX  |  THURSDAY, DECEMBER 1, 2016
    [Glucagon] Diabetes may have a new cure in Platypus venom
    The study found that platypus produces hormone glucagon-like peptide-1 -- normally secreted in the gut of both humans and animals for stimulating the release of insulin to lower blood glucose, but insufficient to maintain proper blood sugar balance Sydney: A hormone produced in the venom of platypus -- an egg-laying mammal native to Australia -- can pave the way for potential new treatments for Type 2 diabetes in humans, researchers have found.
  • TOPIX  |  MONDAY, NOVEMBER 28, 2016
    [Glucagon] Liraglutide doesn't affect gastric emptying in type 1 diabetes
    from the University of Copenhagen in Denmark, and colleagues examined the effect of the glucagon-like peptide-1 receptor agonist liraglutide on counterregulatory responses and GE rate during hypoglycemia in individuals with T1DM in a 12-week randomized trial For individuals with type 1 diabetes mellitus , liraglutide therapy does not affect the rate of gastric emptying during hypoglycemia, according to a study published online Nov. 21 in Diabetes, Obesity and Metabolism.
  • D-MOM  |  MONDAY, NOVEMBER 21, 2016
    [Glucagon] {Kids First, Diabetes Second} Hyperglycemia (High Blood Sugar)
    Causes of high blood sugar include: eating food without the proper amount of corresponding insulin; eating high-sugar-content foods that aren’t matched by the insulin; hormones such as growth hormone, glucagon, and adrenaline; steroids, which are sometimes prescribed for other medical conditions; illness; growth spurts; menstruation; and anger. Recently I shared a section of the book about hypoglycemia (low blood sugar). Today I am sharing a bit about high blood sugar.
  • TOPIX  |  SATURDAY, NOVEMBER 5, 2016
    [Glucagon] New Study Reports Diabetes Medication Could Treat Addiction
    A relatively new class of drugs, glucagon-like peptide-1 receptor agonists, have had much success in the treatment of type 2 diabetes. Now, these drugs may offer support in the treatment of addiction and drug abuse
  • SCOTT'S WEB LOG  |  WEDNESDAY, NOVEMBER 2, 2016
    [Glucagon] Changes in the Price of Insulin, In Graphics (and Vote 'Yes' on 61 in California)
    cWvNRz for my post), that incident was remarkably familiar to people who have to buy insulin, glucagon and supplies needed to manage diabetes. In September 2016, the media was flooded with stories about the rediculously expensive price of EpiPens, which is basically epinephrine used to treat severe allergies (such as when some people get stung by bees or encounter peanuts), as the pens cost more than $600 for a package of two.
  • INSULIN NATION  |  MONDAY, OCTOBER 31, 2016
    [Glucagon] Dual-Hormone ILet Poised to Begin FDA Testing in 2017
    The iLet (formerly known as the “bionic pancreas”) is a compact dual-reservoir pump and controller which takes a CGM reading at five-minute intervals to activate delivery of insulin or glucagon through separate side-by-side cannula lines. The iLet will undergo a more complicated process to FDA clearance than the Medtronic 670G because the FDA requires separate trials into the safety of administering glucagon in micro-doses by automated device.
  • INSULIN NATION  |  FRIDAY, OCTOBER 14, 2016
    [Glucagon] The Pushback Against the Artificial Pancreas
    Even adding glucagon doesn’t begin to cover what the pancreas does to control blood sugar. The pancreas releases insulin and glucagon, hormones that control blood sugar.; The pancreas has several functions, but two hormones specifically for blood sugar control – both insulin and glucagon. There has been some pushback against labeling the Medtronic 670G an “artificial pancreas”.
  • INSULIN NATION  |  MONDAY, OCTOBER 3, 2016
    [Glucagon] How did the 670G and the iLet Perform in Trials?
    The results of two recent trials, as reported by Medscape , show the promise of both the 670G and those of another system, Beta Bionic’s iLet, a combination insulin-and-glucagon system. In contrast, the iLet, by Beta Bionics, is being billed as a more automated artificial pancreas system that incorporates both insulin and glucagon.
  • INSULIN NATION  |  THURSDAY, SEPTEMBER 29, 2016
    [Glucagon] Why I Call the 670G an Artificial Pancreas
    Most experiments focused on a system that automates insulin delivery (single-chamber), but a few focused on a system that delivers both insulin and glucagon (dual-chamber). Second, I looked at historical use of the term “artificial pancreas,” As this 2011 report recapping artificial pancreas experiments shows, the term has been used since the late seventies, long before people seriously believed that glucagon could be used in such a system. Commentary.
  • INSULIN NATION  |  WEDNESDAY, SEPTEMBER 28, 2016
    [Glucagon] FDA Approves First-Ever Artificial Pancreas for Commercial Sale
    After the editor caught his breath from the news, he realized the term might be better reserved for a dual-chamber pump system that includes glucagon. . Ladies and gentlemen, the future is now. The FDA released a press release that matter-of-factly announced what once sounded like science fiction has now become science. Mark it down that on September 28, 2016, the first artificial pancreas system gained approval for commercial sale in the United States.
  • INSULIN NATION  |  TUESDAY, SEPTEMBER 27, 2016
    [Glucagon] Novo Nordisk Recalls More than 70,000 Glucagon Kits
    The injectable glucagon kit is considered a weapon of last resort in combatting a bout of hypoglycemia. In fact, many people who care for those with Type 1 choose to call 911 and forgo using the glucagon kits altogether. These kits are not considered user-friendly, as they often require someone who may not be comfortable with needles to mix the glucagon solution and inject it into someone who may be unconscious…oh, and all during a crisis situation.
  • OUR DIABETIC LIFE  |  WEDNESDAY, SEPTEMBER 21, 2016
    [Glucagon] Rise Up
    Not as bad as some others, but we don't have an extra $500/mo to pay for insulin, and then the pump supplies, forget having glucagon - every month, until we reach our deductible. I remember when Glucagon was $100 per dose. I just received glucagon from our mail order pharmacy. They billed our insurance $500 a piece for our glucagon. If you came here for an epiphany on how we can fix the Health Care System in the United States, I apologize forthwith.
  • D-MOM  |  MONDAY, SEPTEMBER 19, 2016
    [Glucagon] {Type 1 Tuesday} September 2016
    Glucagen is in the orange box, Lilly glucagon is in the red box.). Diabetes Athletes Celebrities D-Mom Moments Diabetes Forecast Magazine Glucagon Product Recalls Type 1 TuesdayHere are some tidbits that I have found interesting and wanted to share… D-Mom Moments. Treating a 50 mg/dL at 1:00 am and arguing with a d-kid who hates the only flavor of juice you have. It was a “Shelby moment” for sure! RECALL ALERT.
  • INSULIN NATION  |  FRIDAY, AUGUST 26, 2016
    [Glucagon] How Stress Hormones Raise Blood Sugar
    All the other hormones—including stress hormones, sex hormones, growth hormones and glucagon—cause the liver to secrete glucose back into the bloodstream. (excerpted from Think Like A Pancreas: A Practical Guide to Managing Diabetes With Insulin by Gary Scheiner MS, CDE, DaCapo Press, 2011). Last weekend I decided to stay up late and watch a scary movie. It had something to do with super-gross vampires who get their jollies by eating the flesh of unsuspecting hotel guests.
  • TOPIX  |  TUESDAY, AUGUST 23, 2016
    [Glucagon] Sanofi Submits New Data on Insulin Glargine/Lixisenatide Pen for Diabetes
    Sanofi has submitted updated information on a pen delivery device as part of its new drug application for the investigational once-daily, fixed-ratio combination of basal insulin glargine 100 U/mL and the glucagon-like peptide-1 receptor agonist lixisenatide for the treatment of adults with type-2 diabetes.
  • TOPIX  |  FRIDAY, AUGUST 12, 2016
    [Glucagon] Ready-to-Use Rescue Pen Successfully Treats Hypoglycemia in Diabetes Patients
    Dasiglucagon, formerly known as ZP4207, is a glucagon peptide analogue with physical and chemical stability in liquid solution Encouraging results have been reported from a phase 2 trial of a single-dose version of dasiglucagon as rescue treatment for severe hypoglycemia in insulin-dependent patients with type-1 diabetes.
  • D-MOM  |  MONDAY, AUGUST 8, 2016
    [Glucagon] {Kids First, Diabetes Second} Tips For Navigating The School Day
    Stock the supply kit with a blood glucose meter and test strips, fast-acting sugar for treating low blood sugar, glucagon, and snacks and water in case they are there for a long time. This is the first of three monthly excerpts about taking type 1 diabetes to school. In the coming months I’ll discuss talking to other kids about diabetes and the dreaded school party.
  • TOPIX  |  THURSDAY, AUGUST 4, 2016
    [Glucagon] Adlyxin Gets FDA Approval to Treat Type 2 Diabetes
    Adlyxin is a glucagon-like peptide-1 receptor agonist, a hormone that helps normalize blood sugar levels Over time, high blood sugar levels can increase the risk for serious complications, including heart disease, blindness and nerve and kidney damage.
  • JOSLIN DIABETES CENTER  |  TUESDAY, AUGUST 2, 2016
    [Glucagon] Back to School with Diabetes | The Basics
    Do you have prescriptions for your insulin, syringes, pen needles, testing supplies, ketone strips and glucagon? Will you keep glucagon available and who will you teach to use it? This month the Joslin Blog is highlighting stories about preparing to go back to school. This story was originally posted on Aug. 1, 2011. Starting a new grade, new school or beginning college can be very stressful even without having diabetes.
  • INSULIN NATION  |  FRIDAY, JULY 22, 2016
    [Glucagon] Glucagon the Sole Focus of a Bionic Pancreas Trial
    Glucagon – it’s not just for emergencies anymore. Recently, a team of researchers at the Massachusetts General Hospital Diabetes Center in Boston conducted a trial that focused exclusively on the automated delivery of glucagon to see if the treatment could prevent hypoglycemia and generally keep study participants in a desired range of blood sugar control. In other words, glucagon did its job to regulate everyday blood sugar swings and counter insulin.
  • TOPIX  |  TUESDAY, JULY 19, 2016
    [Glucagon] American Diabetes Association is a Joint Plaintiff in Lawsuit, Filed Today, to Fight.
    The policy prohibits Army CYSS staff from administering insulin or glucagon and from assisting with carbohydrate counting, which effectively excludes all children with diabetes from access to Army CYSS programs
  • D-MOM  |  MONDAY, JULY 18, 2016
    [Glucagon] {Kids First, Diabetes Second} Sharing the Diagnosis
    Go over the signs and symptoms of low blood sugar, including treatment using the “rule of 15s” (see chapter 4), how and when to use glucagon, signs and symptoms of high blood sugar, and when to check for ketones. In the last excerpt from Kids First, Diabetes Second I shared a description of that first night on our own caring for our child with diabetes. Today I talk about how to share the diagnosis with other children, family, and caregivers. Sharing the Diagnosis.
  • TOPIX  |  MONDAY, JULY 4, 2016
    [Glucagon] Antidiabetic effects discovered in the appetite hormone CART
    The study shows that the appetite hormone CART not only controls the sensation of satiety, but it also helps increase insulin secretion and decrease glucagon production. CART is a hormone that has mainly been studied in the brain's centre for appetite control
  • INSULIN NATION  |  THURSDAY, JUNE 30, 2016
    [Glucagon] Massachusetts School Diabetes Care is Very Nurse-Centered
    Metropolitan Boston is home to institutions housing world-class diabetes care clinics and research facilities, yet Massachusetts is one holdout where school glucose testing, administration of insulin, and even emergency glucagon injections must be performed by or directly supervised by a school nurse. The bill also allows trained non-medical professionals to administer glucagon in emergency situations, again with parental permission.
  • TOPIX  |  SUNDAY, JUNE 12, 2016
    [Glucagon] Liraglutide enhances high-dose insulin treatment in Type 2 diabetes
    The addition of the glucagon-like peptide 1 receptor agonist liraglutide improves short-term outcomes and treatment satisfaction in patients who have uncontrolled Type 2 diabetes despite high doses of insulin, shows a randomised trial. The 35 patients assigned to receive subcutaneous injections of liraglutide 1.8 mg/day achieved better glycaemic control and a decrease in weight, relative to the 36 given a placebo injection, report Ildiko Lingvay and colleagues
  • JOSLIN DIABETES CENTER  |  MONDAY, JUNE 6, 2016
    [Glucagon] Managing Diabetes Care at Camp
    Speak with your child’s health care provider about low dose glucagon as an option for treating low blood sugars at night. Photo by Arthur Pollock. Last week we talked about how to choose a camp when your child has diabetes, and this week we will discuss how to help your child manage their diabetes at camp. Attending summer camp is similar to going on vacation or other times when there is a significant change in your child’s daily routine and planning is the key. Diabetes Camps.
  • INSULIN NATION  |  WEDNESDAY, JUNE 1, 2016
    [Glucagon] Substandard Type 1 Diabetes Care in Utah School Alleged
    State statutes and regulations permit students to self-administer diabetes medications, school officials to administer emergency glucagon, and school nurses to delegate insulin injections and pump adjustments. Students in grades 8 and higher can sometimes possess “epi-pens, asthma inhalers, glucagon, diabetic supplies and pancreatic enzymes” for self-administration.
  • JOSLIN DIABETES CENTER  |  WEDNESDAY, MAY 25, 2016
    [Glucagon] A Life Of Diabetes: Part 2
    Before I went on the CGM which is probably 15 or 20 years ago, once every couple of months [my wife would have to] give me glucagon. And so she gave me the glucagon, and we were fine. Anyway, Gordon put me on a CGM and my wife has not had to give me glucagon once since then.
  • TOPIX  |  MONDAY, MAY 23, 2016
    [Glucagon] Albumedix tech key to Chinese efforts to develop once-a-week diabetes drug
    The collaboration - financial terms of which were not disclosed - will use Albumedix' albumin to extend the half-life of a modified glucagon-like-peptide albumin conjugate called Albenatide that is being developed for the Chinese market. Albenatide was developed by Changshan and partner ConjuChem using the latter firm's drug affinity complex technology
  • D-MOM  |  MONDAY, MAY 9, 2016
    [Glucagon] Diabetes on the Racetrack: For Charlie Kimball It’s A Numbers Game
    The person who changes his inside front tire is trained to give both insulin and glucagon through his suit into his thigh. You would be amazed at how quickly they pull into and out of the pit and I am sure that needing insulin or glucagon would slow down the pit stops considerably. Disclosure: I participated in the Future of Diabetes Summit hosted by Novo Nordisk.
  • TOPIX  |  SUNDAY, MAY 8, 2016
    [Glucagon] Research Suggests Diabetes Drug Acts Differently from Previous Theories
    The researchers found that metformin does not limit the action of the hormone glucagon, specifically glucagon-stimulated glucose production from the liver A Mayo Clinic study suggests laboratory findings do not tell the whole story of how the diabetes drug metformin works to limit the level of glucose in the blood.
  • INSULIN NATION  |  MONDAY, APRIL 4, 2016
    [Glucagon] Bigfoot’s Artificial Pancreas Could Hit the Market by 2018
    There are several companies and groups of researchers racing to bring an artificial pancreas to market, be it one that automates insulin delivery or one that does this and provides glucagon, as well. One of the more intriguing entrants into this race is Bigfoot Biomedical, which grew out of a DIY artificial pancreas project created by co-founder Bryan Mazlish. In 2015, Bigfoot made a splash by acquiring the pump manufacturing assets of the now-defunct Asante Solutions.
  • D-MOM  |  MONDAY, MARCH 28, 2016
    [Glucagon] The AAA’s of Diabetes Management
    Hopefully they can show that it lowers A1c’s, reduces diabetic ketoacidosis (DKA), reduces severe hypoglycemia requiring medical attention and the use of rescue glucagon kits, reduces long term complications such as diabetic retinopathy and neuropathy, and reduces incredibly costly hospital stays. I was recently asked what I hope for in terms of diabetes management 10 years from now or when Q goes to college in (gah!) seven years.
  • INSULIN NATION  |  MONDAY, MARCH 7, 2016
    [Glucagon] Nasal Glucagon Proves Effective in Latest Trial
    Anyone who has had to inject glucagon during a crisis would gladly reach for something easier to use, if it were available, but only if that alternative were just as effective in staving off hypoglycemia. Locemia Solutions has been developing an intranasal glucagon that offers the possibility of eliminating glucagon injections, and the company has announced a string of positive results in key safety trials for its product in 2015.
  • TOPIX  |  TUESDAY, MARCH 1, 2016
    [Glucagon] Study compares effectiveness of insulin regimens for patients with uncontrolled type 2 diabetes
    of the University of North Carolina School of Medicine, Chapel Hill, and colleagues compared the outcomes of once-daily injection of basal insulin vs a once-daily injection of the combination of basal insulin degludec and the glucagon-like peptide-1 receptor agonist liraglutide in patients with uncontrolled type 2 diabetes. In a study appearing in JAMA , John B. Buse, M.D., Ph.D.,
  • TOPIX  |  TUESDAY, FEBRUARY 23, 2016
    [Glucagon] G-pen may aid hypoglycemia with type 1 diabetes
    Mini-dose glucagon administered using a stable, ready-to-use G-Pen Mini glucagon may be an effective option for mild to moderate hypoglycemia in adults with type 1 diabetes, according to a study published online Feb. from the Baylor College of Medicine in Houston, and colleagues evaluated mini-dose glucagon in 12 adults with type 1 diabetes using a stable, liquid, ready-to-use preparation
  • INSULIN NATION  |  MONDAY, FEBRUARY 22, 2016
    [Glucagon] The Aftermath of a Fatal Diabetes-Related Accident
    The woman’s 87-year-old passenger was administering glucagon to the driver when first responders arrived, and remarked, “I have to do this a lot when she gets this way.”. Pennsylvania is a state that has a tough “driving while diabetic” law. All first-time driver’s license applicants in the state must answer a series of questions designed to uncover any compromised ability to safely operate a vehicle.
  • INSULIN NATION  |  MONDAY, FEBRUARY 22, 2016
    [Glucagon] The Aftermath of a Fatal Diabetes-Related Accident
    The woman’s 87-year-old passenger was administering glucagon to the driver when first responders arrived, and remarked, “I have to do this a lot when she gets this way.” Pennsylvania is a state that has a tough “driving while diabetic” law. All first-time driver’s license applicants in the state must answer a series of questions designed to uncover any compromised ability to safely operate a vehicle.
  • CANADIAN D-GAL  |  FRIDAY, FEBRUARY 19, 2016
    [Glucagon] Oops, I did it again.
    get a new box of glucagon and learn to mini-gluc myself. I won't apologize for putting the song in your head as you read this post. I couldn't help myself! I did it again. Twice in 14 months I accidentally overdosed on insulin. It sounds so much more badass when I say I OD'd. What I'm really saying is that I'm a f **g turd sandwich. It was Monday night (last week). Ryan got home from work and we were sitting there talking about our days when my Lantus reminder alarm went off on my phone.
  • JOSLIN DIABETES CENTER  |  WEDNESDAY, FEBRUARY 17, 2016
    [Glucagon] Ain’t No Mountain High Enough: Managing Diabetes in High Altitudes (Part I)
    She recommends healthy, easy to eat carbohydrates like granola bars, fast acting glucose, meter and test strips, a glucagon kit in case of emergency, as well as spare insulin and needles. Zack McCune snowboarding in Jackson Hole, Wyoming. Most people think of the beach when they think vacation. But there are many people, especially in the winter, that flock to the mountains for skiing, hiking or just to take in the views.
  • D-MOM  |  MONDAY, FEBRUARY 8, 2016
    [Glucagon] The Stomach Flu…not again!
    I had the glucagon at the ready and was googling and messaging friends trying to remember how to do “mini glucagon.” None of this is medical advice, see the disclaimer below. I was actually in the middle of writing a post about how we deal with diabetes when Q has performances, but I thought the topic of stomach flu would be appropriate this time of year. The stomach flu has hit Q for the third time this winter. And of course it picked the absolute worst day to strike.
  • INSULIN NATION  |  MONDAY, FEBRUARY 1, 2016
    [Glucagon] Filming the ViaCyte Type 1 Cell Experiment
    The pouch holds clusters of immature cells deigned to mature to produce insulin, glucagon, and hormones. The device delivers insulin and glucagon hormones into the circulatory system. Research into possible functional cures for Type 1 diabetes is often open-ended, with no guarantee of success. The same can be said of documentary filmmaking, since the outcome of the story being told is often unknown when filming begins.
  • INSULIN NATION  |  MONDAY, FEBRUARY 1, 2016
    [Glucagon] Filming the ViaCyte Type 1 Stem Cell Experiment
    The pouch holds clusters of immature beta cells, glucagon, and nutrients for the cells. The device delivers insulin and glucagon hormones into the circulatory system. Research into possible functional cures for Type 1 diabetes is often open-ended, with no guarantee of success. The same can be said of documentary filmmaking, since the outcome of the story being told is often unknown when filming begins.
  • INSULIN NATION  |  MONDAY, JANUARY 25, 2016
    [Glucagon] Glucagon Patch Performs Well in Phase II Trial
    In 2015, the pharmaceutical company Zosano Pharma conducted a Phase II trial on a glucagon patch to test the patch’s safety and efficiency. Researchers found that applying two glucagon patches was just as effective at combating hypoglycemia as two intramuscular injections of a glucagon solution. Also, Lilly acquired the rights to a nasal glucagon spray that has proven very effective in human trials.
  • INSULIN NATION  |  MONDAY, JANUARY 25, 2016
    [Glucagon] Glucagon Patch Performs Well in Phase II Trial
    In 2015, the pharmaceutical company Zosano Pharma conducted a Phase II trial on a glucagon patch to test the patch’s safety and efficiency. Researchers found that applying two glucagon patches was just as effective at combating hypoglycemia as two intramuscular injections of a glucagon solution. Also, Lilly acquired the rights to a nasal glucagon spray that has proven very effective in human trials.
  • INSULIN NATION  |  MONDAY, JANUARY 25, 2016
    [Glucagon] Glucagon Patch Performs Well in Phase II Trial
    In 2015, the pharmaceutical company Zosano Pharma conducted a Phase II trial on a glucagon patch to test the patch’s safety and efficiency. Researchers found that applying two glucagon patches was just as effective at combating hypoglycemia as two intramuscular injections of a glucagon solution. Also, Lilly acquired the rights to a nasal glucagon spray that has proven very effective in human trials.
  • TOPIX  |  SATURDAY, JANUARY 9, 2016
    [Glucagon] Duration of type I diabetes affects glucagon and glucose responses to insulin-induced hypoglycemia.
    The glucagon response to hypoglycemia, which fulfills a primary role toward restoring the plasma glucose level, is blunted or absent in most patients with type I diabetes. To identify predictive factors for this abnormality and for the capability of glycemic counterregulation, we investigated the relationship between the duration of diabetes and glucagon and glucose responses to insulin-induced hypoglycemia
  • JOSLIN DIABETES CENTER  |  FRIDAY, JANUARY 8, 2016
    [Glucagon] Caregivers 101: What to Do When Caring for a Child with Type 1 Diabetes
    Glucagon to treat an extremely low blood glucose level. Caring for someone’s child who has type 1 diabetes is a big responsibility. That’s why the Pediatrics team at Joslin Diabetes Center offers caregivers classes , specifically tailored for people who watch over children with type 1 diabetes; people like teachers, grandparents and babysitters. Educator Heidi Quinn, M.S., L.D.N.,
  • CANADIAN D-GAL  |  MONDAY, JANUARY 4, 2016
    [Glucagon] old school: Lows vs. Highs
    I've never been hospitalized or ever used glucagon. I didn't think lows vs. highs were a thing until I had a few comments back in response to my post on D-hacks. First, since I know I have a few readers not completely consumed with diabetes like myself and other T1's, let me explain: I will assume you already understand the basics of keeping blood sugar in a very unrealistic margin. Ergo, many highs and many lows will inevitably ensue.
  • INSULIN NATION  |  TUESDAY, DECEMBER 29, 2015
    [Glucagon] 10 Big Deals in Type 1 Treatment in 2015
    Nasal glucagon proved safe for kids. The human trials conducted by Locemia Solutions provided hard evidence that the days of injectable glucagon might be numbered. Making glucagon treatment more user-friendly could make the difference between riding out a bad low at home and taking a trip to the hospital. Let’s hope they come to praise nasal glucagon, not to bury it. If a good time existed to have Type 1 diabetes, this would be it.
  • INSULIN NATION  |  TUESDAY, DECEMBER 29, 2015
    [Glucagon] 10 Big Deals in Type 1 Treatment in 2015
    Nasal glucagon proved safe for kids. The human trials conducted by Locemia Solutions provided hard evidence that the days of injectable glucagon might be numbered. Making glucagon treatment more user-friendly could make the difference between riding out a bad low at home and taking a trip to the hospital. Let’s hope they come to praise nasal glucagon, not to bury it. If a good time existed to have Type 1 diabetes, this would be it.
  • INSULIN NATION  |  TUESDAY, DECEMBER 29, 2015
    [Glucagon] 10 Big Deals in Type 1 Treatment in 2015
    New insulin formulations don’t eliminate the risk of hypoglycemia, sadly, so that’s why it’s big news that… Nasal glucagon proved safe for kids. The human trials conducted by Locemia Solutions provided hard evidence that the days of injectable glucagon might be numbered. Making glucagon treatment more user-friendly could make the difference between riding out a bad low at home and taking a trip to the hospital. Let’s hope they come to praise nasal glucagon, not to bury it.
  • TOPIX  |  FRIDAY, DECEMBER 18, 2015
    [Glucagon] Nasal spray may give diabetics faster treatment for low blood sugar
    The trial results showed that the nasal spray is nearly as effective in treating hypoglycemia as the only option currently available, a glucagon powder that must be mixed with water, drawn into a syringe and then injected into muscle A new nasal spray might make rescue care easier for diabetics who are woozy or even unconscious due to severe low blood sugar, a new clinical trial suggests.
  • INSULIN NATION  |  TUESDAY, DECEMBER 15, 2015
    [Glucagon] The 2015 Type 1 Naughty and Nice List
    Locemia invested a lot of time and money into creating a nasal glucagon formula that has done really well in human trials. the leader in injectable glucagon, to come in and buy them up. Dear Lilly, please don’t pull a “Who Killed the Electric Car” fast one with this easy-to-use glucagon, or you will end up on the naughty side of the ledger in 2016. Santa Claus and the NSA aren’t the only ones making lists and checking them twice.
  • INSULIN NATION  |  TUESDAY, DECEMBER 15, 2015
    [Glucagon] The 2015 Type 1 Naughty and Nice List
    Locemia invested a lot of time and money into creating a nasal glucagon formula that has done really well in human trials. the leader in injectable glucagon, to come in and buy them up. Dear Lilly, please don’t pull a “Who Killed the Electric Car” fast one with this easy-to-use glucagon, or you will end up on the naughty side of the ledger in 2016. Santa Claus and the NSA aren’t the only ones making lists and checking them twice.
  • INSULIN NATION  |  THURSDAY, DECEMBER 10, 2015
    [Glucagon] What if the School Nurse is Busy?
    Also, by a 2015 amendment to state law, a parent or guardian may authorize a school employee without a nursing license to administer glucagon injections if a school nurse is unavailable to do so. This has been the state of things, except for the glucagon provision adopted by the New Hampshire Legislature in July of this year, since the most recent technical advisory issued by the Department of Education on the subject in February 2009.
  • INSULIN NATION  |  THURSDAY, DECEMBER 10, 2015
    [Glucagon] What if the School Nurse is Busy?
    Also, by a 2015 amendment to state law, a parent or guardian may authorize a school employee without a nursing license to administer glucagon injections if a school nurse is unavailable to do so. This has been the state of things, except for the glucagon provision adopted by the New Hampshire Legislature in July of this year, since the most recent technical advisory issued by the Department of Education on the subject in February 2009.
  • INSULIN NATION  |  WEDNESDAY, DECEMBER 9, 2015
    [Glucagon] The Patchwork Problem of School Diabetes Care
    According to the American Diabetes Association, 29 states and the District of Columbia permit teachers, administrative personnel, and coaches to administer insulin injections and emergency glucagon, if staff are given proper training. Glucagon is considered an emergency life-saving medication, which under Maine law can be administered by a lay person. Glucagon is covered under the same set of state education department rules which address Epipens and asthma inhalers.
  • INSULIN NATION  |  WEDNESDAY, DECEMBER 9, 2015
    [Glucagon] The Patchwork Problem of School Diabetes Care
    According to the American Diabetes Association, 29 states and the District of Columbia permit teachers, administrative personnel, and coaches to administer insulin injections and emergency glucagon, if staff are given proper training. Glucagon is considered an emergency life-saving medication, which under Maine law can be administered by a lay person. Glucagon is covered under the same set of state education department rules which address Epipens and asthma inhalers.
  • TOPIX  |  TUESDAY, DECEMBER 8, 2015
    [Glucagon] Review of new once-weekly Type 2 diabetes drugs
    Once-weekly glucagon-like peptide-1 receptor agonists differ in their efficacy and safety profiles, according to new research by the University of Leicester. Compared to other once-weekly GLP-1RAs which are licensed and available, dulaglutide 1.5mg and once weekly exenatide showed the greatest reduction of HbA1c and fasting plasma glucose
  • TOPIX  |  TUESDAY, DECEMBER 8, 2015
    [Glucagon] No clear choice among newly available once-weekly diabetes medications
    A systematic evidence review and meta-analysis fails to clarify which once-weekly glucagon-like peptide-1 receptor agonist treatments have the most favorable safety and efficacy profile for treating type 2 diabetes. The newly-available medications vary in terms of cardiometabolic efficacy and adverse effects and direct comparisons are needed to better inform physician prescribing
  • OUR DIABETIC LIFE  |  MONDAY, NOVEMBER 2, 2015
    [Glucagon] Type 1 Diabetes looks like.
    It’s a school principal injecting glucagon into a student who is on the ground, unresponsive from a low blood sugar. A blond boy who just finished third grade and has been losing weight. His parents think it’s from a growth spurt, but he's pale. Something isn't right. It’s a 23-year-old woman who is starting her career in journalism and lately, she is always thirsty. She keeps extra sodas in her drawer at work and a water bottle with her everywhere she goes.
  • INSULIN NATION  |  WEDNESDAY, OCTOBER 28, 2015
    [Glucagon] Could Formoterol be the New Glucagon?
    This doesn’t mean formoterol will be replacing glucagon anytime soon. This study would be just the first step to proving the drug controlled hypoglycemia as well as glucagon. It would also need to be tested against glucagon in head-to-head trials. Nearly 100 years ago, researchers discovered a new drug that changed diabetes care forever. Unfortunately, after the discovery of insulin, there hasn’t been that many other drug breakthroughs to report on in the last century.
  • INSULIN NATION  |  WEDNESDAY, OCTOBER 28, 2015
    [Glucagon] Could Formoterol be the New Glucagon?
    This doesn’t mean formoterol will be replacing glucagon anytime soon. This study would be just the first step to proving the drug controlled hypoglycemia as well as glucagon. It would also need to be tested against glucagon in head-to-head trials. The post Could Formoterol be the New Glucagon? Nearly 100 years ago, researchers discovered a new drug that changed diabetes care forever.
  • THE D-LOG CABIN  |  SATURDAY, OCTOBER 24, 2015
    [Glucagon] A Rendevous With the Artificial Pancreas
    The side table was stocked with 4 glucagon kits, testing stuff, Dexcom stuff, 8 glucose liquids, 4 large jars of glucose tabs and other random diabetes supplies.(I Last weekend, my dreams came true. Well, kind of.It was a joyous thing, to get off from class and coast off into parts unknown, the weekend entirely free from school and kid and spouse and life and blahdeblah.a kind of weekend getaway, as it were.
  • INSULIN NATION  |  FRIDAY, OCTOBER 16, 2015
    [Glucagon] Lilly Acquires Rights to Nasal Glucagon
    One of the biggest pharmaceutical companies is placing a big bet that nasal glucagon is going to get FDA approval in the near future. has acquired the worldwide rights to a nasal glucagon product being developed by Locemia Solutions, according to a recent press release. Lilly, it should be noted, currently has the corner on the market for the standard mix-and-inject glucagon kits.
  • INSULIN NATION  |  FRIDAY, OCTOBER 16, 2015
    [Glucagon] Lilly Acquires Rights to Nasal Glucagon
    One of the biggest pharmaceutical companies is placing a big bet that nasal glucagon is going to get FDA approval in the near future. has acquired the worldwide rights to a nasal glucagon product being developed by Locemia Solutions, according to a recent press release. Lilly, it should be noted, currently has the corner on the market for the standard mix-and-inject glucagon kits.
  • INSULIN NATION  |  FRIDAY, OCTOBER 16, 2015
    [Glucagon] Lilly Acquires Rights to Nasal Glucagon
    One of the biggest pharmaceutical companies is placing a big bet that nasal glucagon is going to get FDA approval in the near future. has acquired the worldwide rights to a nasal glucagon product being developed by Locemia Solutions, according to a recent press release. Lilly, it should be noted, currently has the corner on the market for the standard mix-and-inject glucagon kits. The post Lilly Acquires Rights to Nasal Glucagon appeared first on Insulin Nation.
  • JOSLIN DIABETES CENTER  |  WEDNESDAY, OCTOBER 14, 2015
    [Glucagon] Joslin Patient Lobbies for Diabetes Rights in School
    The bill in New Hampshire stated that only nurses could administer the Glucagon shot,” said Skye. Without a nurse present to administer Glucagon in the instance of hypoglycemia, Skye had to compromise her extracurricular interests to keep herself healthy. Skye’s work alongside her parents resulted in Senate Bill 71, which allows Glucagon injections to be administered by trained school employees when a nurse is not present. Bill 71 isn’t the first Glucagon law of its kind.
  • TOPIX  |  SATURDAY, OCTOBER 10, 2015
    [Glucagon] Lilly Acquires Phase III Intranasal Glucagon from Locemia Solutions
    Intranasal glucagon, which is currently in Phase III clinical trial testing, could be the first needle-free rescue treatment for severe hypoglycemia. Intranasal glucagon uses a proprietary glucagon nasal powder formulation that is delivered in an emergency situation using a single-use, ready-to-use device
  • TOPIX  |  FRIDAY, OCTOBER 9, 2015
    [Glucagon] Lilly buys rights to intranasal diabetes treatment
    Intranasal glucagon could be "the first needle-free rescue" for the hypoglycemia and "an important innovation for people with diabetes" condition, Lilly said. Financial terms were not disclosed
  • TOPIX  |  TUESDAY, SEPTEMBER 29, 2015
    [Glucagon] Diabetes medication can reduce food intake
    A new dissertation at Sahlgrenska Academy shows that medication used for type-2 diabetes wich mimics the gut-brain hormone glucagon-like peptide-1, can affect the brain's reward system and reduce the intake of food Many studies have focused on how much we eat when we are hungry, but sometimes we eat just to feel better.
  • DIABETES IN CONTROL  |  WEDNESDAY, SEPTEMBER 23, 2015
    [Glucagon] Gap in Scientific Knowledge About Some Diabetes Drugs
    In particular, their survey found that one such treatment has the hitherto unrecognized potential to activate receptor sites for the hormone, glucagon. A gap in scientific knowledge about a family of drugs that are used to treat type 2 diabetes has been highlighted in a new study.
  • NINJABETIC  |  MONDAY, SEPTEMBER 21, 2015
    [Glucagon] My Scariest Moment Yet
    My wife grabbed the glucagon shot and woke my son up to call 911 while she gave me the dose. It was 4AM on Sunday, August 16th. My wife woke up to use the restroom and upon returning to bed noticed that I had the blankets thrown off of me and I was covered in sweat. She knew I was low and grabbed my glucometer to check my bg. She tried to wake me up so I could prick my own finger but I was not responsive so she did it.
  • TOPIX  |  THURSDAY, SEPTEMBER 17, 2015
    [Glucagon] Study highlights possible knowledge gap over effects of some diabetes drugs
    Scientists have found that some drugs from a group of anti-diabetic treatments may, in certain circumstances, act on glucagon receptors in the body, meaning that they could also potentially enable the release of sugar into the bloodstream. A gap in scientific knowledge about a family of drugs that are used to treat Type 2 diabetes has been highlighted in a new study
  • YOUR DIABETES MAY VARY  |  THURSDAY, SEPTEMBER 17, 2015
    [Glucagon] T1D Exchange Abstracts at European Association for the Study of Diabetes (EASD)
    From: https://t1dexchange.org/pages/t1d-exchange-to-present-several-abstracts-at-the-51st-european-association-for-the-study-of-diabetes-easd-annual-meeting/ Here are some introductory paragraphs from their release to tempt you to read more: New Intranasal Glucagon Effective in Children and Adolescents. Preliminary clinical trial data have demonstrated that a new, user-friendly, needle-free delivery system is as effective in children and adolescents as the injected form of glucagon.
  • DIABETES IN CONTROL  |  MONDAY, SEPTEMBER 7, 2015
    [Glucagon] Editor's Note, DCMS #257
    There is a pump to deliver insulin and a pump to deliver glucagon, however, the “brains” of the system is the glucose reading device. The diabetes newsletters and services have all been carrying articles about the artificial pancreas. There are three basic components to the device. Without the brains, then the other two components just work randomly with dangerous consequences.
  • TOPIX  |  SATURDAY, AUGUST 22, 2015
    [Glucagon] L. reuteri supplements may modulate gut insulin metabolism: RCT
    reuteri tablets for four weeks was also associated with 76% and 43% increases in glucose-stimulated glucagon-like peptides -1 and -2 release, wrote researchers from Germany, Denmark and the US Tablets containing Nutraceutix's L. reuteri strain and its patented BIO-tract delivery technology were found to increase insulin secretion by 49%, according to findings published in Diabetes Care. Daily administration of L.
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