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| | TOPIX
APRIL 19, 2016 [Tolbutamide] Metformin Safer for Heart Than Other Common Type 2 Diabetes Drugs: Study
Metformin reduced the risk of dying from heart attack and stroke by about 30 percent to 40 percent compared with other commonly used drugs called sulfonylureas, such as glibenclamide, glimepiride, glipizide and tolbutamide, researchers report Metformin, the most frequently prescribed standalone drug for type 2 diabetes, is better for the heart than its closest competitors, a large analysis suggests.
| | DIABETES HEALTH
MAY 13, 2011 [Tolbutamide] Danish Study Reports Three Diabetes Drugs Best for Lowering Cardiovascular Risk
Other common diabetes medications, including glimepiride, glibenclamide (glyburide), glipizide, and tolbutamide, were linked to a higher risk of death both from all causes and from heart attack and stroke A Danish study of 107,806 adults taking various diabetes medications has found that three drugs are the most effective at lowering the risk of cardiovascular disease and death: metformin, gliclazide (not marketed in the US), and repaglinide (Prandin).